2,6-Dimethyl-4-pyridone (2.1 g.) in 15 ml. HCl, 6.5 g. ICl in 5 mi., and 100 ml. H2O heated 3 hrs. at 90° and the product dild. with 300 ml. H2O and cooled gave 6.4 g. 2,6-dimethyl-3,5-diiodo-4-pyridone (I), m. 259-61°. Similarly, 1 g. 2,6,4-Me2(H2N)C5H2N yielded 79% 4-NH2 analog of I,m. 155°; HCl salt, m. 258° (decompn.); 0.2 g. 4,2,6-Me2(HS)C5H2N yielded 0.55 g. 4-SH analog of I, m. 247° (decompn.).
